Super Collagen + Vitamin C

Key Benefits

• ✓ NeoCell Super Collagen+C provides 6,000 mg of hydrolyzed Type 1 and Type 3 collagen per serving — the two most abundant and functionally critical collagen types in the human body. Type 1 is the primary collagen of skin (dermis), tendons, ligaments, cornea, and bone matrix, while Type 3 is essential for the elastic resilience of skin, blood vessel walls, and hollow organs.
• ✓ NeoCell's proprietary hydrolysis process breaks whole collagen into specific low-molecular-weight peptides (particularly the Pro-Hyp and Hyp-Gly dipeptides), which are small enough to be absorbed intact through the intestinal wall and transported via the bloodstream to target tissues — most importantly the dermis, where they are recognized by fibroblast receptors.
• ✓ Upon reaching dermal fibroblasts, the collagen peptides activate a highly specific signaling cascade: they bind to DDR (discoidin domain receptor) and integrin receptors on fibroblast surfaces, stimulating the upregulation of endogenous collagen genes (COL1A1, COL1A2, COL3A1), effectively instructing skin cells to produce significantly more of their own collagen infrastructure.
• ✓ The clinically validated 92% skin hydration result cited on the label reflects NeoCell's own branded clinical study, in which participants reported measurable improvements in skin moisture. The mechanism involves both increased dermal collagen density (reducing water-loss pathways through the extracellular matrix) and stimulation of hyaluronic acid production — the skin's primary humectant — by the same fibroblast activation pathway.
• ✓ Joint support: Type 1 and 3 collagen provide the tensile strength of tendons and ligaments surrounding joints, and supplemental collagen peptides have been shown to accumulate preferentially in cartilage tissue following oral administration. Studies using radiolabelled collagen peptides confirm uptake in articular cartilage — the tissue most relevant to joint comfort and mobility.
• ✓ Bone health: Type 1 collagen constitutes approximately 90% of bone's organic matrix (osteoid) — the framework into which hydroxyapatite calcium crystals are deposited. Collagen supplementation supports the synthesis of this organic scaffold, complementing calcium and Vitamin D supplementation by addressing the structural protein matrix rather than only the mineral component of bone.
• ✓ Vitamin C (ascorbic acid) is included as the biochemically essential cofactor for collagen synthesis. Specifically, Vitamin C is required by prolyl-4-hydroxylase and lysyl hydroxylase — the enzymes that add hydroxyl groups to proline and lysine residues in procollagen chains. This hydroxylation is mandatory for the formation of stable inter-chain hydrogen bonds that create the triple-helix collagen structure. Without Vitamin C, procollagen cannot mature into functional collagen and is rapidly degraded.

Recommended Usage

Scientific Backing