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Fish oil

Price
Ksh2299.00

Fish oil

Key Benefits

  • Each 1200 mg softgel provides 360 mg of combined EPA and DHA — the clinically active omega-3 fraction responsible for cardiovascular, neurological, and anti-inflammatory benefits. The remaining oil consists of other naturally occurring fatty acids from the fish source.
  • EPA and DHA reduce very-low-density lipoprotein (VLDL) synthesis in the liver by inhibiting diacylglycerol acyltransferase (DGAT), the rate-limiting enzyme in triglyceride synthesis, thereby reducing the hepatic export of triglyceride-rich lipoproteins.
  • Improves the omega-6 to omega-3 ratio in cellular membranes — the modern diet typically has a 15:1 to 20:1 ratio (heavily omega-6 dominant), while the evolutionary optimum is approximately 4:1. Fish oil supplementation corrects this imbalance, shifting the inflammatory setpoint toward resolution.
  • Supports arterial compliance and endothelial function by increasing nitric oxide bioavailability in blood vessel walls — nitric oxide is the primary vasodilatory molecule that prevents arterial stiffness and maintains healthy blood pressure.
  • Reduces markers of systemic inflammation including C-reactive protein (CRP), interleukin-6 (IL-6), and TNF-alpha — inflammatory biomarkers strongly correlated with coronary artery disease, type 2 diabetes, and metabolic syndrome risk.
  • The rapid release softgel format facilitates fast dissolution in the gastrointestinal tract, ensuring timely delivery of fatty acids to intestinal lymphatic absorption channels (chylomicron formation) for efficient uptake.
  • The FDA's qualified health claim states: 'Supportive but not conclusive research shows that consumption of EPA and DHA omega-3 fatty acids may reduce the risk of coronary heart disease' — the claim printed on this product's label.

Recommended Usage

Scientific Backing

  • Heart Disease Risk: The ORIGIN trial (NEJM, 2012) and subsequent meta-analyses confirm omega-3 supplementation significantly reduces cardiovascular mortality in high-risk patients, with the strongest effects in individuals with low dietary fish intake (common across East Africa).
  • Blood Pressure: A meta-analysis of 70 RCTs (Miller et al., Journal of Hypertension, 2014) found fish oil supplementation produced a dose-dependent reduction in systolic blood pressure of approximately 1.5 mmHg — clinically meaningful at population scale.
  • Inflammation: A 2017 review in Nutrients confirmed EPA and DHA reduce CRP levels by 10–20% in populations with elevated baseline inflammation, with effects independent of lipid-lowering.
  • Membrane Incorporation: Research confirms that 8–12 weeks of supplementation is required to appreciably change erythrocyte and tissue membrane omega-3 index, which is the biologically relevant measure of omega-3 status.